Intractable Tufted Angioma Associated with Kasabach-Merritt Syndrome

Intractable Tufted Angioma Associated with Kasabach-Merritt Syndrome

Received May 11, 2012, Revised June 14, 2012, Accepted for publication July 12, 2012 *These authors are contributed equally to this work. Corresponding author: Kyoung Chan Park, Department of Dermatology, Seoul National University Bundang Hospital, 82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam 463-707, Korea. TEL: 82-31-787-7311, Fax: 82-31-787-4058, E-mail: [email protected] This is an Open Acce...

Tufted angioma associated with Kasabach-Merritt phenomenon: a therapeutic challenge.

Fig. 1. (A) Tufted angioma involving the chin in a one-month-old child. (B) The patient at 2 months of age showing a subtle increase in tumour size and decrease in platelet count. (C) A subtle residual lesion on the chin of the patient at the age of 5 years. Tufted angioma (TA) is an infrequently seen, benign vascular tumour, which was first described in 1949 (1). It is characterized clinically...

Kasabach-merritt syndrome arising from tufted angioma successfully treated with systemic corticosteroid.

We report a case of Kasabach-Merritt syndrome arising from a tufted angioma successfully treated with systemic corticosteroid. A 2-month-old male infant presented with a palm-sized, erythematous induration on his left pubis. The lesion was diagnosed as tufted angioma histopathologically. After 1 month, the lesion suddenly expanded to the abdomen and scrotum. Initial laboratory tests were consis...

Efficiency of an mTOR Inhibitor in Kasabach-Merritt Phenomenon with Indolent Tufted Angioma: A Case Report.

Kasabach-Merritt syndrome.

Hemangiomas of infancy are usually congenital lesions. Occasionally they are associated with microangiopatbic bemolytic anaemia, thrombocytopenia, and a consumptive coagulopathy. This is most often associated with cavernous hemangiomas. Thrombocytopenia associated with giant cavernous hemangiomas was first noted by Kasabach and Merritt in 1940. As the primary mechanism of platelet destruction i...